Archive: 2025/12

Dec, 24 2025

The Purple Book: Understanding Biosimilars and Interchangeability from the FDA

The FDA's Purple Book is the official guide to biosimilars and interchangeable biological drugs. Learn how it works, what interchangeability means, and how state laws affect substitution at the pharmacy.

Dec, 22 2025

Cardiovascular Combination Generics: What You Can Take and What You Should Know

Cardiovascular combination generics combine multiple heart medications into one pill to improve adherence, cut costs, and simplify treatment. Learn which combos are available, how they compare to brand names, and what to ask your doctor.

Dec, 21 2025

Systemic Antifungals and Statins: What You Need to Know About Dangerous Drug Interactions

Systemic antifungals like ketoconazole and posaconazole can dangerously increase statin levels, leading to muscle damage or rhabdomyolysis. Learn which combinations to avoid, safer alternatives, and what to do if you're on both.

Dec, 20 2025

How to Identify Class-Wide vs. Drug-Specific Safety Alerts in Medications

Learn how to distinguish between class-wide and drug-specific safety alerts in medications. Understand FDA criteria, real-world examples, and practical steps to avoid prescribing errors.

Dec, 19 2025

International Drug Safety Monitoring Systems Explained

International drug safety monitoring systems track adverse drug reactions globally to protect public health. Learn how WHO's VigiBase, EudraVigilance, and national programs work-and why disparities in reporting still exist.

Dec, 18 2025

Fulminant Hepatic Failure from Medications: How to Recognize It in an Emergency

Fulminant hepatic failure from medications is sudden, deadly, and often preventable. Learn how acetaminophen and other common drugs can cause liver collapse - and what to do before it’s too late.

Dec, 16 2025

Alcohol and Diabetes Medications: How to Avoid Dangerous Low Blood Sugar

Drinking alcohol while on diabetes meds can cause dangerous low blood sugar-even hours later. Learn how to avoid life-threatening hypoglycemia with science-backed safety tips.

Dec, 15 2025

Manufacturing Changes and Generic Approval: What Triggers FDA Re-Evaluation

Learn what manufacturing changes trigger FDA re-evaluation for generic drugs, how the approval process works, and why companies struggle to improve production without costly delays.

Dec, 15 2025

How the FDA Ensures Generic Drug Quality During Manufacturing

The FDA ensures generic drug quality through strict cGMP standards, unannounced inspections, and rigorous testing at every manufacturing stage. Learn how these rules keep generics safe, effective, and affordable.

Dec, 15 2025

Effective Patent Life: Why Market Exclusivity for Drugs Is Shorter Than You Think

Effective patent life is the real window of market exclusivity for drugs - often just 10 to 15 years - after accounting for years spent in clinical trials and FDA review. Discover why patents don't last 20 years in practice.

Dec, 12 2025

Multiple Sclerosis: How the Immune System Attacks the Nervous System

Multiple sclerosis is an autoimmune disease where the immune system attacks myelin in the brain and spinal cord, causing nerve damage and symptoms like fatigue, vision loss, and numbness. Learn how it happens and what treatments are changing lives.

Dec, 11 2025

Second-Generation Antihistamines: Safer, Non-Drowsy Options for Allergy Relief

Second-generation antihistamines like cetirizine, loratadine, and fexofenadine offer effective allergy relief without the drowsiness of older drugs. Learn how they work, their real-world pros and cons, and what to expect.